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Letter

What do we mean by viability in terms of 'viable but non-culturable' cells?

Details

Citation

Mu D, Du Z, Chen J, Austin B & Zhang X (2021) What do we mean by viability in terms of 'viable but non-culturable' cells?. Environmental Microbiology Reports, 13 (3), pp. 248-252. https://doi.org/10.1111/1758-2229.12953

Abstract
In a recent Opinion article (¡®Viable But Non©\Culturable Cells¡¯ are Dead, https://doi.org/10.1111/1462-2920.15463), Song and Wood (2021) argued the cells that can rejuvenate and reconstitute infections are not part of a dormancy continuum. Instead, only persister cells are dormant and capable of re©\growth, whereas viable but non©\culturable (VBNC) cells are dead. We argue against this conclusion in light of multiple previous publications. Thus, we discuss the relations of death/non©\viability, dormancy and the culturability of Viable But Non©\Culturable (VBNC) cells. In essence, we address the issue about what is meant by ¡®viability¡¯?

Journal
Environmental Microbiology Reports: Volume 13, Issue 3

StatusPublished
Publication date01/06/2021
Publication date online26/04/2021
Date accepted by journal11/04/2021
eISSN1758-2229